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    Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents

  • In This Issue
    Proceedings of the National Academy of Sciences, Volume 122, Issue 27, July 2025. <br/>... Read more »
  • Building confidence in models for complex barrier systems for radionuclides
    Proceedings of the National Academy of Sciences, Volume 122, Issue 27, July 2025. <br/>The modeling and simulation of the Cement–clay Interaction–Diffusion field (CI-D) experiment at the Mont Terri site in Switzerland presented here demonstrates that it is possible to capture the multiscale physical and chemical features of natural and ...... Read more »
  • The global persistence of work from home
    Proceedings of the National Academy of Sciences, Volume 122, Issue 27, July 2025. <br/>Work from home (WFH) surged worldwide during the COVID-19 pandemic, then partially receded as the pandemic subsided. Using our Global Survey of Working Arrangements covering dozens of countries, we find that average WFH rates among college-educated ...... Read more »
  • Fundamental toughening landscape in soft–hard composites: Insights from a minimal framework
    Proceedings of the National Academy of Sciences, Volume 122, Issue 27, July 2025. <br/>SignificanceNature presents a grand blueprint for material design by organizing soft and hard components into sophisticated multiscale and hierarchical architectures. Despite unprecedented progress, the most fundamental toughening mechanisms of soft–hard ...... Read more »
  • Detecting environmentally dependent developmental plasticity in fossilized individuals
    Proceedings of the National Academy of Sciences, Volume 122, Issue 27, July 2025. <br/>SignificanceTraits are determined by internal factors such as genetics and plastic responses to the external environment. Being able to distinguish which factor most affected the evolution of each trait frames the capacity for organisms to adapt to... Read more »
  • Tandem ssDNA in neutrophil extracellular traps binds thrombin and regulates immunothrombosis
    Proceedings of the National Academy of Sciences, Volume 122, Issue 27, July 2025. <br/>SignificanceThe role of neutrophil extracellular traps (NETs) in promoting thrombosis has been well recognized; however, the precise molecular mechanisms about how NETs function as blood coagulation scaffolds remain underexplored, particularly the ...... Read more »
  • PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosis
    Proceedings of the National Academy of Sciences, Volume 122, Issue 27, July 2025. <br/>SignificanceLipid droplets (LDs), unique cellular organelles, are enclosed by a monolayer of phospholipids. Whether phosphoinositides, signposts of cellular organelles, exist on LDs remains to be unequivocally determined. CIDE proteins are essential for ...... Read more »

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UNIVERSITY OF MICHIGAN

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UNIVERSITY OF SOUTHAMPTON

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SciTechDaily

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    SciTechDaily

  • This Virtual Forest Calms Your Brain – No Hiking Required
    A new study reveals that forest bathing doesn’t have to happen outdoors to be effective—when recreated in virtual reality with visuals, forest sounds, and natural scents, it can ease stress, improve mood, and even enhance memory. Participants who experienced a fully immersive VR forest showed stronger emotional and cognitive benefits... Read more »
  • The 200-Year Tree Delay That Could Cost Us the Forests We Love
    Forests are falling dangerously behind in the race against climate change. A new study reveals that tree populations typically need 100 to 200 years to respond to warming—far too slow for today’s rapid shifts. Ancient pollen records and spectral analysis show that while the climate races ahead, forests are stuck... Read more »
  • Ancient Mud Just Shattered a 750,000-Year-Old Ice Myth
    Evidence of algae growth and climate simulations reveal the Arctic had seasonal ice, not a permanent ice shelf, for much of the past 750,000 years. These insights challenge long-standing theories. For a long time, researchers have debated whether a thick, continuous ice shelf once blanketed the entire Arctic Ocean during... Read more »
  • Scientists Grow 400+ Brain Cell Types in a Dish – Could This Be the Key to Curing Alzheimer’s?
    Scientists have successfully grown over 400 different types of nerve cells from stem cells in the lab—a groundbreaking step toward replicating the complexity of the human brain. By systematically experimenting with combinations of morphogens and genetic triggers, researchers mimicked the incredible diversity of neurons found in various regions of the... Read more »
  • New Once-a-Week Shot Promises Life-Changing Relief for Parkinson’s Patients
    A once-a-week shot from Australian scientists could spare people with Parkinson’s the grind of taking pills several times a day. The tiny, biodegradable gel sits under the skin and releases steady doses of two key medicines all week long, aiming for steadier symptom control, fewer side effects, and a much... Read more »
  • Alzheimer’s Iceberg: 200+ Hidden Proteins That May Be Quietly Destroying Memory
    A groundbreaking study has revealed over 200 misfolded proteins in the brains of aging rats with cognitive impairment, far beyond the well-known amyloid and tau plaques. These newly identified proteins don’t form the typical clumps seen under microscopes, making them harder to detect but potentially just as dangerous. Scientists believe... Read more »
  • The Milky Way May Be Surrounded by 100 Hidden Galaxies
    Astronomers may be on the verge of uncovering a long-lost galactic population. Using ultra-high-resolution simulations and sophisticated modeling, researchers at Durham University predict that the Milky Way could be surrounded by up to 100 previously undetected satellite galaxies. These faint, elusive “orphan galaxies” may have been stripped of their dark... Read more »

JOHNS HOPKINS UNIVERSITY

MESON STARS

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NEUROSCIENCE NEWS

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    Neuroscience News

  • Why Women Face Higher Alzheimer’s Risk
    Women are nearly twice as likely as men to develop Alzheimer’s disease, a disparity that can’t be fully explained by longevity alone. Researchers are exploring biological differences, focusing on X chromosome-linked genes and hormonal shifts like menopause.... Read more »
  • Blood Sugar, Not Age, Drives Sexual Health Decline in Men
    A new study reveals that metabolic health, particularly modest increases in blood sugar, plays a bigger role than age or testosterone in declining sexual and reproductive function in men. Researchers tracked 117 healthy men over six years, assessing hormones, semen quality, erectile function, and blood sugar.... Read more »
  • Oxytocin Protects Mood During Sleep Loss
    New research suggests oxytocin, the so-called “love hormone,” may help protect women from mood disturbances caused by sleep disruption and hormonal changes during postpartum and menopause. In a controlled study, women with higher oxytocin levels before sleep fragmentation reported fewer mood symptoms the following day.... Read more »
  • Weekly Injection Could Revolutionize Parkinson’s Treatment
    Researchers have developed a long-acting weekly injection that delivers steady doses of levodopa and carbidopa, potentially transforming care for Parkinson’s disease. The biodegradable injectable maintains consistent drug levels, reducing the need for multiple daily pills and improving patient adherence.... Read more »
  • Gene Key to MS Immune Regulation Discovered
    New research has identified the gene Egr-1 as a critical regulator of immune balance, offering hope for autoimmune disease therapies. In a mouse model of multiple sclerosis, loss of Egr-1 led to reduced regulatory T cell activity and heightened inflammation. T... Read more »
  • Maternal Depression Linked to Weaker Bonds
    A comprehensive global review confirms that maternal depression undermines parenting, impairing mother-infant bonding and reducing sensitivity to a child’s needs. Researchers analyzed nearly a decade of observational studies, finding consistent links between depressive symptoms and lower involvement, commitment, and emotional connection.... Read more »
  • Study Challenges Link Between Football and Brain Protein Buildup
    A new study questions whether playing youth football leads to harmful protein buildup in the brain. Researchers examined 174 donated brains, including former high school and college players, and found no link between contact sports and excess tau protein in a key memory region.... Read more »

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