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    Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents

  • In This Issue
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>... Read more »
    Source: Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents | Published: November 18, 2025 - 8:00 am
  • Quantification of redox thermodynamics shifts within coacervates
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceThe earliest enzymes are thought to have formed through the assembly of macromolecules into disordered, secondary phases known as coacervates. While these phases are believed to have played a role in early catalysis, the underlying mechanisms ...... Read more »
    Source: Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents | Published: November 14, 2025 - 8:00 am
  • Digital tools for analyzing nondiffeomorphic shapes
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceA key limitation to using geometric morphometrics is the lack of high-fidelity tools. The most powerful methods in geometric morphometrics require that the meshes are similar, but not all geometric data satisfy this requirement. The Euler ...... Read more »
    Source: Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents | Published: November 14, 2025 - 8:00 am
  • The Kinship Formula: Inferring the numbers of all kin from any structured population projection model
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceWe derive the Kinship Formula which yields the number of any kin from any structured population projection model. This formula should prove important across fields utilizing structured population dynamics. For example, it can assist ecologists ...... Read more »
    Source: Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents | Published: November 14, 2025 - 8:00 am
  • Neurodevelopmental disorder–linked Argonaute mutations permit delayed RISC formation and unusual shortening of miRNAs by 3′→5′ trimming
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>Mutations in Argonaute proteins (AGOs) cause Argonaute syndrome, a neurodevelopmental disorder (NDD), yet the underlying molecular mechanism remains unclear. We determined cryo-electron microscopy (cryo-EM) structures of wild-type (WT) AGO1 and the ...... Read more »
    Source: Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents | Published: November 14, 2025 - 8:00 am
  • Advancing stochastic 3-SAT solvers by dissipating oversatisfied constraints
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceHard decision problems, in computational complexity theory known as NP-complete, are of universal importance. From a conceptual perspective, an efficient solution to one such complete problem is tantamount to solving any other in the wide ...... Read more »
    Source: Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents | Published: November 14, 2025 - 8:00 am
  • mTORC1 regulates autophagosomal components recycling through SNX16 phosphorylation
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceAutophagosomal components recycling (ACR) is a recently discovered recycling process responsible for the recycling of autophagosome outer membrane components from autolysosomes. The optimal function of this process is imperative for proper ...... Read more »
    Source: Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents | Published: November 14, 2025 - 8:00 am

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UNIVERSITY OF SOUTHAMPTON

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SciTechDaily

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    SciTechDaily

  • ● Global Study Exposes Massive Fraud in Mathematics Publishing
    Fraud driven by flawed metrics threatens mathematics, say researchers urging change. An international group of researchers led by Ilka Agricola, a mathematics professor at the University of Marburg in Germany, has examined widespread misconduct in the publication of mathematical research. Working on behalf of the German Mathematical Society (DMV) and... Read more »
    Source: SciTechDaily | Published: November 24, 2025 - 2:51 am
  • ● Princeton’s Breakthrough Qubit Could Finally Make Quantum Computing Practical
    Princeton engineers extended qubit lifetimes using a new tantalum-silicon design that sharply cuts energy loss. The improvement could enable large, stable quantum processors capable of real-world problem solving. Princeton engineers have taken a significant step toward developing useful quantum computers by creating a superconducting qubit that remains stable for three... Read more »
    Source: SciTechDaily | Published: November 24, 2025 - 2:16 am
  • ● Scientists Just Discovered How Rabies Hijacks Human Cells
    Researchers found that rabies virus uses a shape-shifting protein to hijack RNA and control vital cell functions. Viruses are astonishingly efficient, able to take over our cells and control essential processes using only a tiny amount of genetic material. Scientists have long wondered how such small viruses manage to achieve... Read more »
    Source: SciTechDaily | Published: November 24, 2025 - 1:41 am
  • ● This Strange Chameleon Fooled Scientists for 150 Years
    Scientists identified two new chameleon species through genetic analysis. Museum DNA helped clarify long-standing taxonomic confusion. Madagascar is widely recognized as the home of chameleons. Over 40% of all documented chameleon species are found on this island off the East African coast, including the so-called Pinocchio chameleon, which scientists have... Read more »
    Source: SciTechDaily | Published: November 24, 2025 - 1:06 am
  • New Study Suggests That an Ancient Chinese Herbal Remedy Could Improve Fertility
    New research reveals how the traditional Chinese formula Jinfeng Pills can biologically restore a thin endometrium, a persistent contributor to infertility. A new study published in the journal Reproductive and Developmental Medicine has identified how a traditional Chinese herbal formula may help restore endometrial receptivity in cases of thin endometrium... Read more »
    Source: SciTechDaily | Published: November 23, 2025 - 10:20 pm
  • 7-Year Study Reveals Rheumatoid Arthritis Begins Long Before Symptoms
    The seven-year study identifies early warning signs that may allow doctors to detect the disease before it develops, potentially sparing patients years of pain and disability. Scientists have found that rheumatoid arthritis (RA) does not begin when pain becomes noticeable. Instead, it starts quietly many years earlier. RA is a... Read more »
    Source: SciTechDaily | Published: November 23, 2025 - 9:45 pm
  • 70-Year Mystery Solved: Scientists Finally Discover How Lifesaving Pregnancy Drug Really Works
    A Penn-led research team has uncovered how hydralazine, one of the oldest blood pressure medications and a standard treatment for preeclampsia, functions at the molecular level. In the process, they made an unexpected finding: it can also stop the growth of aggressive brain tumors. Over the last 70 years, hydralazine... Read more »
    Source: SciTechDaily | Published: November 23, 2025 - 9:10 pm

JOHNS HOPKINS UNIVERSITY

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NEUROSCIENCE NEWS

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    Neuroscience News

  • AI Reveals Lions Don’t Just Roar, They Have a Second Call
    A new study reveals African lions produce two types of roars, overturning long-held assumptions and opening the door to more precise wildlife monitoring. Using machine learning, researchers automatically distinguished between full-throated and newly identified intermediary roars with over 95% accuracy, eliminating much of the human bias in vocal identification.... Read more »
    Source: Neuroscience News | Published: November 23, 2025 - 6:08 pm
  • What Triggers Tantrums? Sensory Overload May Be To Blame
    New research reveals a distinct brain activity signature in children who become overwhelmed by sensory input such as noise, touch, or bright lights. Using functional MRI, scientists found that overly sensitive children show reduced activation in outward-facing sensory and motor networks while increasing activation in inward-focused networks tied to cognition... Read more »
    Source: Neuroscience News | Published: November 21, 2025 - 9:53 pm
  • Brain Circuit That Forces Behavior Into “Repeat Mode” Identified
    A new study has identified a specific brain circuit that can push behavior into a compulsive “repeat mode,” forcing mice to continue digging and sniffing even when rewards are available. The circuit links the nucleus accumbens to the hypothalamus and then to the lateral habenula, a region involved in processing... Read more »
    Source: Neuroscience News | Published: November 21, 2025 - 8:59 pm
  • Genetics Plus Heart Health Markers Sharpen Dementia Risk
    New research shows that dementia risk is best predicted by combining genetic vulnerability with cardiovascular disease markers, revealing a more precise and actionable way to identify who is most likely to develop the condition. While genes such as APOE4 and family history contribute heavily, equally powerful are modifiable factors like... Read more »
    Source: Neuroscience News | Published: November 21, 2025 - 7:55 pm
  • Supplement Shows Promise in Blocking Amyloid in Alzheimer’s
    A new study shows that oral arginine, a naturally occurring amino acid, can significantly suppress amyloid-β aggregation in Alzheimer’s disease models. Researchers found that arginine not only prevented Aβ42 from clumping but also reduced plaques and inflammation in mouse and fruit fly models carrying Alzheimer’s-related mutations.... Read more »
    Source: Neuroscience News | Published: November 21, 2025 - 7:03 pm
  • Early Brain Activity Differences Predict Addiction Risk in Boys vs Girls
    A large-scale analysis of nearly 1,900 children found that those with a family history of substance use disorder show early differences in how their brains transition between activity states, long before any drug exposure. Girls with family history showed increased transition energy in introspective networks, suggesting greater difficulty shifting out... Read more »
    Source: Neuroscience News | Published: November 21, 2025 - 6:37 pm
  • Screen Time in Tweens Predicts ADHD, Slower Brain Growth
    A large, two-year study of nearly 12,000 children found that higher screen time at ages 9–10 predicts an increase in ADHD symptoms, independent of a child’s starting symptom level. Brain imaging revealed that heavy screen use is associated with smaller cortical volume and disrupted development in regions critical for attention,... Read more »
    Source: Neuroscience News | Published: November 21, 2025 - 5:13 pm

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