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VAN DER BILT UNIVERSITY

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PNAS – SCIENTIFIC JOURNALS

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    Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents

  • In This Issue
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>... Read more »
  • Nanomaterial-induced mitochondrial biogenesis enhances intercellular mitochondrial transfer efficiency
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceMitochondrial dysfunction plays a key role in many diseases, yet treatments to restore function remain limited. Cells naturally transfer mitochondria to help repair damage, but this process is inefficient. Here, we use molybdenum disulfide (...... Read more »
  • Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceTransposable elements (TEs) constitute about half of the vertebrate genome. Previously, we provided evidence that TE silencing by CpG methylation in the germ line and subsequent deamination resulted in strong CpG depletion not only in the TEs... Read more »
  • The dominant sink of oceanic calcium carbonate occurs in undersaturated seawater
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceTo predict the role of oceans in absorbing anthropogenic CO2in the future, it is important to quantify the current budget of calcium carbonate (CaCO3) in oceans. Our study provides an estimate of the CaCO3dissolution rate in global... Read more »
  • A cytoplasmic motif in HLA-E that drives clathrin-mediated endocytosis and VCP-associated postendocytic trafficking
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceBy presenting a conserved self-peptide to NKG2A/C-CD94 receptors on NK cells, nonpolymorphic HLA-E plays a central role in regulating innate immunity. While HLA-E can also present foreign peptides to stimulate protective T cell responses, ...... Read more »
  • Glycan recognition by collectin-11 drives SARS-CoV-2 infectivity and membrane injury of respiratory epithelial cells
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceSARS-CoV-2 infection of the respiratory tract continues to be a health risk even among immunized individuals suggesting that localized factors could maintain viral infection and transmission. Here, we show that although the locally produced ...... Read more »
  • A Bayesian perspective on single-shot laser characterization
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceUltraintense lasers are a key technology behind multiple transformative technologies such as laser-driven particle acceleration or inertial confinement fusion. To date, characterization of these lasers relies mostly on multishot scanning ...... Read more »

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UNIVERSITY OF MICHIGAN

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UNIVERSITY OF SOUTHAMPTON

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SciTechDaily

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    SciTechDaily

  • “Natural Experiment” Reveals Lifelong Cardiac Benefits of Early Sugar Limits
    The findings support the recommendation to minimize added sugars in the diets of pregnant women and infants. A new study published in The BMJ has found that limiting sugar intake during early life is associated with a reduced likelihood of developing major heart conditions later on, including heart attack, heart... Read more »
  • Groundbreaking New Compound Could Treat the World’s Deadliest Infectious Disease
    The world’s deadliest infectious disease urgently requires new and effective antibiotics. Researchers have created a promising new compound that may mark a major step forward in the global effort to combat tuberculosis, the deadliest infectious disease in human history. According to a new study published in Nature, the compound, called... Read more »
  • “Mystery Molecules” Found in Dogs Could Help Humans Live Longer, Healthier Lives
    A large study in pet dogs has uncovered potential new biomarkers of aging that could one day help both dogs and humans live longer, healthier lives. Scientists have long searched for biological indicators, known as biomarkers, that can accurately reflect a person’s true biological age or signal potential health problems... Read more »
  • Jupiter’s Gravity May Explain a 4.5-Billion-Year-Old Meteorite Mystery
    The early growth of the gas giant carved rings that formed primitive meteorites and shaped the architecture of the inner solar system. New research from Rice University reveals that Jupiter played a powerful role in shaping the early solar system. As the giant planet formed, it dramatically altered the structure... Read more »
  • Scientists Unlock Secrets of the Building Blocks of the Universe
    Researchers have moved one step closer to solving one of science’s greatest mysteries—why the universe is filled with matter instead of nothing. Scientists at Indiana University have made a major advance in understanding how the universe came to exist. Their success comes from a collaboration between two large international research... Read more »
  • What If Einstein Was Only Half Right? NASA’s New Test for Dark Energy
    New strategies may soon allow scientists to test dark energy theories within our own solar system, linking cosmic-scale physics to local observation. Science advances through a cycle of proposing theories and rigorously testing them in search of contradictions. This process is especially challenging when dealing with vast, cosmological theories that... Read more »
  • Scientists Solve Decades-Old Puzzle of Electron Emission
    What occurs when electrons escape from a solid material? Though it may appear straightforward, this process has long resisted accurate theoretical explanation, until now. Researchers have finally uncovered the missing piece that completes the puzzle. Picture a frog inside a box with a high opening. Whether it can get out... Read more »

JOHNS HOPKINS UNIVERSITY

MESON STARS

NEW SCIENTIST

NEUROSCIENCE NEWS

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    Neuroscience News

  • How Chemotherapy Triggers Nerve Damage, and How to Stop It
    A new study reveals that chemotherapy-induced nerve pain arises from a stress response in immune cells that triggers inflammation and neurotoxicity. Researchers found that activating a cellular stress sensor called IRE1α causes nerve damage and pain during chemotherapy, but blocking it prevents both in mice.... Read more »
  • Epigenetic Switch to Turn Memories On and Off Created
    Researchers have shown for the first time that flipping an epigenetic “switch” in specific memory-holding neurons can directly alter memory strength. By targeting the gene Arc—which helps neurons adjust their connections—scientists used CRISPR-based tools to either boost or silence its activity in engram cells within the hippocampus.... Read more »
  • How Neurons Feel Force: Uncovering the Physics of Touch
    A groundbreaking study reveals how neurons sense and transmit mechanical forces across their membranes—a key to understanding touch, movement, and development. Using precision laser-based optical tweezers, researchers discovered that tension travels faster in touch-sensing neurons than in movement-sensing ones.... Read more »
  • How the Brain’s Ion Gates Open and Close
    New research reveals how tiny electrical gates in the brain, known as NMDA receptors, control learning, memory, and neuron survival. Using cryo-electron microscopy, scientists captured atomic-level images showing how a natural neurosteroid, 24S-HC, holds these channels wide open, while a synthetic compound locks them partially shut.... Read more »
  • Your Brain “Zones Out” After Poor Sleep To Clean Itself
    New research shows that during moments of lost focus after poor sleep, the brain releases a wave of cerebrospinal fluid (CSF)—the same cleansing process that normally occurs during deep sleep. Using simultaneous EEG and fMRI scans, scientists found that these fluid pulses occur precisely when attention lapses, suggesting the brain... Read more »
  • Football Players Show Subtle Brain Differences Linked to CTE Risk
    Brain scans of former football players revealed subtle differences in brain grooves compared to men who never played contact sports, possibly marking early signs of chronic traumatic encephalopathy (CTE). Researchers found that players had shallower grooves in a key frontal region previously associated with CTE and that years of play... Read more »
  • When Using AI, Users Fall for the Dunning-Kruger Trap in Reverse
    A new study reveals that when interacting with AI tools like ChatGPT, everyone—regardless of skill level—overestimates their performance. Researchers found that the usual Dunning-Kruger Effect disappears, and instead, AI-literate users show even greater overconfidence in their abilities.... Read more »

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