WETENSCHAP EN TECHNOLOGIE BL – 2

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VAN DER BILT UNIVERSITY

SCIENTIFIC AMERICAN

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NATURE

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    Nature

  • Electro-generated excitons for tunable lanthanide electroluminescence
    Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09717-1The electroluminescence emitted from lanthanide fluoride nanocrystals functionalized with ligands is shown to be tunable, providing a method for exciton control in insulating nanocrystal systems and offering a pathway for spectrally precise electroluminescent materials.... Read more »
  • Rewiring an olfactory circuit by altering cell-surface combinatorial code
    Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09769-3In Drosophila, changing the expression of a small set of cell-surface proteins in just one type of olfactory neuron rewires its connections almost entirely to a new postsynaptic partner neuron type, altering the fly’s odour response and courtship behaviour.... Read more »
  • How do genetic association studies rank genes?
    Nature, Published online: 19 November 2025; doi:10.1038/d41586-025-03651-yGenome-wide association studies and rare-variant burden tests are the two main tools for discovering links between genetic variants and traits. Comparisons of their results reveal that they systematically rank genes differently, and models have been developed to explain why. Ultimately, both methods are complementary,... Read more »
  • Hepatic zonation determines tumorigenic potential of mutant β-catenin
    Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09733-1Zonal positioning in the liver determines whether the CTNNB1 oncogene can induce liver cancer.... Read more »
  • Genetic elements promote retention of extrachromosomal DNA in cancer cells
    Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09764-8A combination of genome-wide functional screening, imaging and chromatin profiling identifies a new class of highly prevalent genomic elements that help retain extrachromosomal DNA copies in dividing cells and persist across generations.... Read more »
  • If the AI bubble bursts, what will it mean for research?
    Nature, Published online: 19 November 2025; doi:10.1038/d41586-025-03776-0The rise in artificial-intelligence technologies is unprecedented, but some predict a stock-market crash that could have knock-on effects for funding and jobs.... Read more »
  • Semantic design of functional de novo genes from a genomic language model
    Nature, Published online: 19 November 2025; doi:10.1038/s41586-025-09749-7By learning a semantics of gene function based on genomic context, the genomic language model Evo autocompletes DNA prompts to generate novel genes encoding protein and RNA molecules with defined activities, whose sequences generalize beyond those found in nature.... Read more »

PNAS – SCIENTIFIC JOURNALS

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    Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents

  • In This Issue
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>... Read more »
  • Quantification of redox thermodynamics shifts within coacervates
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceThe earliest enzymes are thought to have formed through the assembly of macromolecules into disordered, secondary phases known as coacervates. While these phases are believed to have played a role in early catalysis, the underlying mechanisms ...... Read more »
  • Digital tools for analyzing nondiffeomorphic shapes
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceA key limitation to using geometric morphometrics is the lack of high-fidelity tools. The most powerful methods in geometric morphometrics require that the meshes are similar, but not all geometric data satisfy this requirement. The Euler ...... Read more »
  • The Kinship Formula: Inferring the numbers of all kin from any structured population projection model
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceWe derive the Kinship Formula which yields the number of any kin from any structured population projection model. This formula should prove important across fields utilizing structured population dynamics. For example, it can assist ecologists ...... Read more »
  • Neurodevelopmental disorder–linked Argonaute mutations permit delayed RISC formation and unusual shortening of miRNAs by 3′→5′ trimming
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>Mutations in Argonaute proteins (AGOs) cause Argonaute syndrome, a neurodevelopmental disorder (NDD), yet the underlying molecular mechanism remains unclear. We determined cryo-electron microscopy (cryo-EM) structures of wild-type (WT) AGO1 and the ...... Read more »
  • Advancing stochastic 3-SAT solvers by dissipating oversatisfied constraints
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceHard decision problems, in computational complexity theory known as NP-complete, are of universal importance. From a conceptual perspective, an efficient solution to one such complete problem is tantamount to solving any other in the wide ...... Read more »
  • mTORC1 regulates autophagosomal components recycling through SNX16 phosphorylation
    Proceedings of the National Academy of Sciences, Volume 122, Issue 46, November 2025. <br/>SignificanceAutophagosomal components recycling (ACR) is a recently discovered recycling process responsible for the recycling of autophagosome outer membrane components from autolysosomes. The optimal function of this process is imperative for proper ...... Read more »

Science News

UNIVERSITY OF MICHIGAN

CODON MAG

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INTERESTING ENGINEERING

UNIVERSITY OF SOUTHAMPTON

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SciTechDaily

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    SciTechDaily

  • Trapping a Single Particle to Reveal Lightning’s First Spark
    A daring new laser-based technique lets researchers trap and charge a single aerosol particle, opening a window into how tiny ice crystals in clouds might store and release electrical energy. As the team discovered, laser photons can knock electrons off these particles one by one, allowing scientists to watch them... Read more »
  • These Breast Cancer Facts Could Save Your Life
    A nursing professor dispels common myths, explains the risks, and highlights promising new treatments. Breast cancer is one of the most commonly diagnosed cancers in the world and remains a major cause of cancer-related illness in the United States. A new case is identified in the U.S. roughly every two... Read more »
  • Hidden Brain Cells May Hold the Key to Alzheimer’s
    Scientists have found a special group of microglia (brain immune cells) that can help protect against Alzheimer’s disease. These protective cells reduce inflammation, slow the buildup of harmful plaques, and may preserve memory and brain function. This discovery not only explains why certain genetic traits reduce Alzheimer’s risk but also... Read more »
  • It’s Not Autism: The Real Tylenol Risk People Keep Overlooking
    Each year, acetaminophen poisoning sends about 56,000 people to U.S. emergency rooms. A CU Anschutz Emergency Medicine toxicology specialist is exploring a new approach to treatment. As social media and news outlets circulate unverified claims about connections between acetaminophen use and autism in children, experts emphasize that the more immediate... Read more »
  • Doctors “Astounded”: Long-Held Belief About Coffee and Heart Rhythm Was Wrong
    In a surprising finding, the first randomized clinical trial revealed that drinking a cup of coffee each day reduces the risk of atrial fibrillation. Regular coffee consumption may actually help protect against atrial fibrillation (A-Fib), a common heart rhythm problem that causes a fast, irregular heartbeat and can increase the... Read more »
  • Scientists Discover Earthquake Faults Can Heal Themselves in Hours
    Scientists have discovered that deep earthquake faults can heal themselves within hours, acting like “quick-set glue” after slow slip events. By recreating high-pressure, high-temperature conditions in the lab, researchers found that quartz grains can rapidly weld back together, restoring strength far faster than previously thought. Deep Fault Healing Breakthrough Earthquake... Read more »
  • Scientists Warn: “Almost Half of the Beaches Will Disappear by the End of the Century”
    Coastal ecosystems are being crushed by rising sea levels linked to urbanization. Beaches across the globe are experiencing a form of “crushing,” a process driven by rising sea levels linked to climate change, along with the growing development of coastal regions. These pressures disrupt the wide variety of species that... Read more »

JOHNS HOPKINS UNIVERSITY

MESON STARS

NEW SCIENTIST

NEUROSCIENCE NEWS

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    Neuroscience News

  • Shocking Disparities: Women Face Higher Risk of ECT
    A large international survey of 858 electroconvulsive therapy recipients found that women are twice as likely as men to receive ECT and experience more adverse effects. Women reported higher rates of memory loss, greater feelings of coercion, and more harmful emotional outcomes, often describing the treatment as retraumatizing.... Read more »
  • Ultra-Thin Finger Patch Recreates Touch With Human-Level Precision
    Engineers have created VoxeLite, the first wearable haptic device capable of matching the sensitivity of the human fingertip. Built as a paper-thin, flexible bandage for the finger, it uses high-density electroadhesive “pixels of touch” to recreate fine textures and directional cues with lifelike accuracy.... Read more »
  • Cannabis Blunts Alcohol Cravings
    A randomized, placebo-controlled trial shows that cannabis with active THC reduces immediate alcohol cravings and lowers drinking levels in heavy-drinking young adults. After smoking THC, participants not only drank less, they waited longer before taking the first sip and reported lower urges to drink.... Read more »
  • Restoring Vision: Temporary Retinal Silencing Reverses Amblyopia
    A new study in mice shows that briefly anesthetizing the retina of the weaker eye can restore its neural influence in the adult visual cortex. The treatment activates a specific burst-firing mode in thalamic neurons, a developmental mechanism that reopens plasticity even after the usual critical period has closed.... Read more »
  • Lithium Fails to Slow Cognitive Decline in Alzheimer’s
    A new meta-analysis of six randomized controlled trials shows that lithium supplementation does not significantly slow cognitive decline in people with mild cognitive impairment or Alzheimer’s disease. While preclinical evidence suggests lithium supports resilience against amyloid and tau pathology, these benefits failed to translate to clinical outcomes using traditional lithium... Read more »
  • Brain’s “Hourglass Timer” Controls the Precise Timing of Movement
    Researchers have discovered how the brain keeps time for precise movements, revealing a neural “hourglass” mechanism between the motor cortex and striatum. The motor cortex sends timing signals that accumulate in the striatum until they reach a threshold that triggers action.... Read more »
  • Maternal Stress Speeds Up Baby Teething
    New research shows that infants whose mothers had higher cortisol levels during late pregnancy experience significantly earlier eruption of primary teeth. Babies of mothers with the highest cortisol levels had, on average, four more teeth by six months than those of mothers with the lowest levels.... Read more »

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