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    Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents

  • In This Issue
    Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. <br/>... Read more »
  • Beyond “non-significant” results: Why and how to test for practical equivalence
    Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. <br/>Reporting comparisons withP≥ 0.05 as showing “no effect” or “no difference” remains one of the most widespread and problematic misinterpretations in the scientific literature. A statistically nonsignificant result shows only that the data do not provide ...... Read more »
  • Unitary representations and von Neumann’s continuous geometries
    Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. <br/>SignificanceWe unveil a striking limitation in von Neumann’s program of modeling quantum logic through continuous geometries. Continuous geometries have natural groups of symmetries, which arise as the unit groups of their coordinate rings. Our main ...... Read more »
  • Overcoming the blood–brain barrier using central nervous system–accessing lipid nanoparticles for enhanced mRNA therapeutics
    Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. <br/>SignificanceSystemic delivery of mRNA to the brain remains a major barrier to treat central nervous system (CNS) diseases because the blood–brain barrier (BBB) severely restricts therapeutic entry. To overcome this challenge, we developed a CNS-accessing ...... Read more »
  • Mechanistic insights into cooperative permeation of glycerol and water through human aquaporin-10
    Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. <br/>SignificanceHuman aquaporin-10 (hAQP10) is a pH regulated transmembrane protein channel that facilitates the transport of glycerol and water across cell membranes. Despite their critical role in lipid metabolism and pathophysiology, a quantitative ...... Read more »
  • Distinct transcriptional logics of catechol siderophore transporters in Pseudomonas aeruginosa for efficient iron acquisition
    Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. <br/>SignificanceIron acquisition is essential forPseudomonas aeruginosasurvival, particularly in iron-depleted host environments. To obtain iron, this pathogen uses siderophores (small, high-affinity iron-binding molecules) and their specific outer membrane ...... Read more »
  • The effectiveness of green place-based industrial policy: Evidence from the Inflation Reduction Act
    Proceedings of the National Academy of Sciences, Volume 123, Issue 33, August 2026. <br/>SignificanceThe Inflation Reduction Act represents the largest U.S. climate investment in history, combining clean energy subsidies with place-based incentives targeting economically distressed communities. We provide evidence on whether these spatially ...... Read more »

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  • This Grain-of-Rice-Sized “Rainbow” Chip Could Transform 6G Communications
    A tiny chip that produces a precisely organized “rainbow” of light could help enable faster, higher-capacity 6G communications and more precise timing for quantum technologies. A microchip about the size of a grain of rice can generate a carefully ordered spectrum of light and convert it into multiple high-frequency electromagnetic... Read more »
  • Physicists Discover Time Crystals Can Communicate Across a Semiconductor
    Separate time crystals inside a semiconductor can “find” each other across surprising distances and lock into the same rhythm. Researchers at TU Dortmund University demonstrated the effect using a semiconductor system in which electron and nuclear spins form continuous time crystals. Their latest experiments, published in Nature Communications, reveal that... Read more »
  • Scientists Finally Solve a 20-Year Mystery About Diamond Melting
    Direct measurements of diamond melting under extreme pressure resolved a long-standing theory-experiment mismatch and could improve both fusion research and planetary models. Diamond is not only a gemstone. This exceptionally hard form of carbon is also used in the tiny capsules that surround fuel in inertial confinement fusion experiments, and... Read more »
  • Common Vape Flavor May Disrupt Early Human Development
    Laboratory tests suggest that vanillin used in e-cigarettes can alter early human stem cell development through the TRPV4 channel. Vanillin, a flavoring chemical commonly used in e-cigarettes, may interfere with early embryonic development, according to laboratory research published August 12, 2026, in Human Reproduction, a leading journal in reproductive medicine.... Read more »
  • Ultra-Processed Foods Linked to 30% Higher Prostate Cancer Risk
    New research adds to growing evidence that ultra-processed foods are linked to health risks. Ultra-processed foods (UPFs) now supply nearly 60% of the calories consumed by U.S. adults and about 70% of those consumed by children. These industrial products include soft drinks, packaged cereals and snacks, and processed meats, and... Read more »
  • More Screen Time, Better Thinking? An 8-Year Study Finds a Surprising Link
    Screen time was associated with better adolescent cognitive processing, while links between physical activity and cognition varied by sex, activity type, and measurement method. A Finnish study following children into adolescence found an unexpected pattern: those who accumulated more screen time from childhood tended to show better cognitive processing as... Read more »
  • A Vast Clean Energy Source May Be Hiding Beneath Australia’s Red Soil
    As the world searches for low-emission energy sources, researchers have identified a potentially important source of clean energy beneath Western Australia’s red soil. Beneath Western Australia’s Pilbara region, vast iron ore deposits contain magnetite that may do more than supply raw material for industry. Research from Edith Cowan University (ECU)... Read more »

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