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VAN DER BILT UNIVERSITY

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    Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents

  • In This Issue
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>... Read more »
  • Nanomaterial-induced mitochondrial biogenesis enhances intercellular mitochondrial transfer efficiency
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceMitochondrial dysfunction plays a key role in many diseases, yet treatments to restore function remain limited. Cells naturally transfer mitochondria to help repair damage, but this process is inefficient. Here, we use molybdenum disulfide (...... Read more »
  • Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceTransposable elements (TEs) constitute about half of the vertebrate genome. Previously, we provided evidence that TE silencing by CpG methylation in the germ line and subsequent deamination resulted in strong CpG depletion not only in the TEs... Read more »
  • The dominant sink of oceanic calcium carbonate occurs in undersaturated seawater
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceTo predict the role of oceans in absorbing anthropogenic CO2in the future, it is important to quantify the current budget of calcium carbonate (CaCO3) in oceans. Our study provides an estimate of the CaCO3dissolution rate in global... Read more »
  • A cytoplasmic motif in HLA-E that drives clathrin-mediated endocytosis and VCP-associated postendocytic trafficking
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceBy presenting a conserved self-peptide to NKG2A/C-CD94 receptors on NK cells, nonpolymorphic HLA-E plays a central role in regulating innate immunity. While HLA-E can also present foreign peptides to stimulate protective T cell responses, ...... Read more »
  • Glycan recognition by collectin-11 drives SARS-CoV-2 infectivity and membrane injury of respiratory epithelial cells
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceSARS-CoV-2 infection of the respiratory tract continues to be a health risk even among immunized individuals suggesting that localized factors could maintain viral infection and transmission. Here, we show that although the locally produced ...... Read more »
  • A Bayesian perspective on single-shot laser characterization
    Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificanceUltraintense lasers are a key technology behind multiple transformative technologies such as laser-driven particle acceleration or inertial confinement fusion. To date, characterization of these lasers relies mostly on multishot scanning ...... Read more »

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UNIVERSITY OF MICHIGAN

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UNIVERSITY OF SOUTHAMPTON

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SciTechDaily

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    SciTechDaily

  • El Niño’s Rapid Rise Could Trigger Planet-Wide Weather Whiplash
    Scientists predict that global warming could make El Niño far more powerful and consistent than before. High-resolution models show that within decades, the Pacific may hit a tipping point, locking Earth into intense, rhythmic climate cycles. This synchronization of global systems could increase extreme weather and rainfall variability around the... Read more »
  • Invisible, Skyscraper-Sized Waves Found to Be “Eating Away” at Greenland’s Glaciers
    Scientists have uncovered how massive underwater waves triggered by iceberg calving secretly fuel glacier melt in Greenland. Iceberg calving takes place when large sections of ice detach from the edges of glaciers and plunge into the ocean. This natural event is one of the main contributors to the rapid ice... Read more »
  • The Universe Just Sent Us a Spooky Bat Signal
    A ghostly “cosmic bat” nebula, glowing red with newborn stars, has been captured by ESO’s telescope in Chile. Just in time for Halloween, astronomers have captured the image of a bat-like figure soaring across the night sky over the European Southern Observatory’s (ESO’s) Paranal site in Chile. Using its exceptionally... Read more »
  • AI Is Learning to Be Selfish, Study Warns
    Researchers at Carnegie Mellon University have discovered that certain AI models can develop self-seeking behavior. A new study from Carnegie Mellon University’s School of Computer Science suggests that as artificial intelligence systems become more advanced, they also tend to behave more selfishly. Researchers from the university’s Human-Computer Interaction Institute (HCII)... Read more »
  • MIT’s Radical New Method Lets Scientists See Inside Atoms
    MIT physicists have unveiled a groundbreaking way to explore the hidden interior of atoms, without the need for massive particle colliders. By binding radium atoms with fluoride to form radium monofluoride molecules, they used the atom’s own electrons as probes to momentarily enter the nucleus and carry back subtle “messages”... Read more »
  • Scientists Unlock the Cancer-Fighting Power of the Rarest Element on Earth
    Texas A&M researchers have unlocked a new way to harness astatine-211, a rare and powerful isotope that may revolutionize cancer treatment. Astatine is the rarest naturally occurring element on the planet and among the least explored in the periodic table, largely because its name, derived from the Greek word for... Read more »
  • Amazon Scorpion Venom Shows Promise as Next-Generation Breast Cancer Drug
    Researchers at the University of São Paulo have discovered a molecule in arachnid venom that behaves like a commonly used chemotherapy drug for treating the disease, with preliminary findings presented at FAPESP Week France. The venom of a scorpion native to the Amazon rainforest may hold the key to a... Read more »

JOHNS HOPKINS UNIVERSITY

MESON STARS

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NEUROSCIENCE NEWS

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    Neuroscience News

  • Rotating Brain Waves Help the Mind Refocus After Distraction
    Neuroscientists have discovered that when the brain is distracted, coordinated “rotating” waves of neural activity help it steer back to focus. Using electrical recordings in animals, the team found that neurons in the prefrontal cortex synchronize in circular patterns—like starlings in flight—to recover from cognitive interruptions.... Read more »
  • How “Frazzled” Keeps the Brain Wired for Lightning-Fast Communication
    Scientists have uncovered a key role for the protein “Frazzled” in building and maintaining the rapid neural connections that allow fruit flies to react in milliseconds. When Frazzled is missing, neurons lose vital gap junctions, slowing communication and weakening muscle responses.... Read more »
  • Human Mind Prefers Simple Explanations Over Complex Truths
    New research shows that people tend to prefer simple explanations even when complex ones are more accurate. The study found that individuals focus mainly on visible or known causes while neglecting hidden or absent ones, leading to oversimplified reasoning.... Read more »
  • Newly Mapped Brain Circuit Reveals How Memories Stay Stable During Learning
    A new study reveals how brain circuits between the entorhinal cortex and hippocampus stabilize memories during learning. Researchers found that synchronized signals between excitatory and inhibitory neurons in these regions help strengthen “place maps,” ensuring memories remain consistent even as new information is learned.... Read more »
  • Common Antidepressant Eases Core Symptoms Within Two Weeks
    A new analysis of the PANDA clinical trial reveals that sertraline, one of the most prescribed antidepressants, improves key emotional symptoms of depression—such as sadness, self-loathing, and suicidal thoughts—within just two weeks of treatment. Using network analysis to assess individual symptoms, researchers found that the drug also eased anxiety early... Read more »
  • Toddler Gut Bacteria Linked to Childhood Anxiety and Depression
    A new study suggests that a child’s gut microbiome at age 2 may influence their emotional health years later. Researchers found that higher levels of bacteria from the Clostridiales order and Lachnospiraceae family were linked to stronger connectivity across emotion-related brain networks and a higher risk of anxiety and depression... Read more »
  • $2 Saliva Test Could Help Detect Depression and Schizophrenia
    Scientists have developed a portable biosensor that can detect levels of BDNF, a protein linked to mental health conditions such as depression, schizophrenia, and bipolar disorder. The flexible, low-cost device analyzes a drop of saliva in under three minutes, offering a fast, affordable, and noninvasive diagnostic tool.... Read more »

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