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VAN DER BILT UNIVERSITY

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    Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents

  • In This Issue
    Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025. <br/>... Read more »
  • Correction for Fernandez Velasco et al., Expert navigators deploy rational complexity–based decision precaching for large-scale real-world planning
    Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025. <br/>... Read more »
  • HCK regulates NLRP12-mediated PANoptosis
    Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025. <br/>SignificanceThe cytosolic innate immune sensor NLRP12 induces inflammatory cell death, PANoptosis, in response to homeostatic disruptions and infection. NLRP12-mediated PANoptosis has been implicated in hemolytic and inflammatory diseases, but the ...... Read more »
  • The distribution of highly deleterious variants across human ancestry groups
    Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025. <br/>SignificanceA major focus of human genetics is to identify severely pathogenic variants, both to help diagnose patients and as an entry point into understanding disease mechanisms. To that end, it is often argued that we should sequence... Read more »
  • Learning to estimate sample-specific transcriptional networks for 7,000 tumors
    Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025. <br/>SignificanceNetwork estimation is essential for understanding the structure and function of biological systems, but current statistical approaches fail to capture intersubject heterogeneity or cross-modality information flow, both of which are needed for ...... Read more »
  • The cortical critical power law balances energy and information in an optimal fashion
    Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025. <br/>SignificanceHow neural populations in the brain represent sensory information is one of the central questions in neuroscience. To ensure robustness against noise, it is widely believed that the neural representation must avoid the so-called fractal state, ...... Read more »
  • Neuron–astrocyte associative memory
    Proceedings of the National Academy of Sciences, Volume 122, Issue 21, May 2025. <br/>SignificanceRecent experiments have challenged the belief that glial cells, which compose at least half of brain cells, are just passive support structures. Despite this, a clear understanding of how neurons and glia work together for brain function... Read more »

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UNIVERSITY OF MICHIGAN

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UNIVERSITY OF SOUTHAMPTON

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SciTechDaily

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    SciTechDaily

  • Perpendicular Planet: A 90° Orbit Over Twin Suns Leaves Scientists Stunned
    Astronomers have discovered one of the weirdest planetary systems yet: a possible planet, 2M1510 b, appears to orbit over the poles of two brown dwarfs in a sharply tilted path—almost perpendicular to their own orbit. This freakish setup, unlike anything in our solar system, was detected not by a dip... Read more »
  • Europa’s Fractured Ice Is Leaking Clues From a Hidden Ocean Below
    Webb telescope data, backed by lab experiments, reveal Europa’s icy shell is a dynamic landscape, with ice that crystallizes and reshapes under cosmic bombardment. In chaos terrains like Tara Regio, the presence of strange chemicals—including table salt and carbon dioxide—suggests that materials from a deep subsurface ocean are leaking to... Read more »
  • AI Cracks Mars Mystery: 500,000 Streaks Solved Without a Drop of Water
    A Martian mystery decades in the making might finally be solved! The streaky slopes spotted on Mars since the 1970s—once suspected to be signs of salty water and potential habitability—are now thought to be the result of dry dust avalanches triggered by wind, impacts, or shifting rocks. Mysterious Streaks on... Read more »
  • Wild Orangutans Display Language Complexity Once Thought Uniquely Human
    Wild orangutans use multi-layered recursive vocal patterns that vary with danger, challenging the idea that only humans use complex, structured communication. In a groundbreaking study from the University of Warwick, researchers have discovered that wild orangutans produce vocalizations with a layered complexity once believed to be unique to human communication.... Read more »
  • New Research Reveals the Brain Learns Differently Than We Thought
    Research provides new insights into how the brain forms habits and explains why they can be so difficult to break. Neuroscientists at the Sainsbury Wellcome Centre (SWC) at UCL have discovered that the brain uses two distinct systems to learn through trial and error. This is the first time a... Read more »
  • MIT Breakthrough: Star-Shaped Brain Cells Could Be the Secret Behind Human Memory
    Astrocytes, once thought to be the brain’s housekeepers, may actually be silent powerhouses of memory. MIT scientists have proposed a bold new model where these star-shaped cells, with their intricate networks and calcium signaling, help store massive amounts of information, potentially far more than neurons alone could. This theory could... Read more »
  • Graphene Is Stretchable? Physicists Make “Miracle Material” Bend Like Never Before
    Ultra clean, air-free measurements reveal a new property of graphene. Graphene is often called a “miracle material” because it is both mechanically extremely strong and highly conductive, making it ideal for many technological applications. Physicists at the University of Vienna, led by Jani Kotakoski, have now made a breakthrough: by... Read more »

JOHNS HOPKINS UNIVERSITY

MESON STARS

NEW SCIENTIST

NEUROSCIENCE NEWS

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    Neuroscience News

  • T Cells Found Living in Healthy Brains
    Contrary to long-standing beliefs, T cells—key immune cells—have been discovered in the healthy brains of both mice and humans. These cells, previously thought to only enter the brain during disease, were most concentrated in a region that regulates hunger and thirst.... Read more »
  • Blocking Opioid Receptors May Restore Healthy Dopamine Balance
    New research identifies a promising strategy for correcting dopamine imbalances in the brain using a drug that blocks kappa opioid receptors (KOR). In mouse models with a rare mutation that causes dopamine to leak abnormally, KOR blockers reduced this leakage and restored normal behavior.... Read more »
  • Kindness Sparks Cooperation by Boosting Social Connectedness
    New research reveals that everyday niceness—like warm tones, smiles, and active listening—can significantly improve teamwork and increase willingness to cooperate. These small acts foster a sense of social connectedness, which serves as the bridge between kindness and collaboration.... Read more »
  • One Molecule to Sleep and Wake: A New Brain Switch Discovered
    Researchers studying the tiny roundworm C. elegans have uncovered a surprising mechanism by which a single brain signal controls both falling asleep and waking up. The chemical messenger FLP-11 activates a receptor called DMSR-1 in different neurons to either silence wakefulness or shut down sleep, acting as a biological on-off... Read more »
  • How Personality Shapes Emotional Intimacy
    While neuroticism is strongly associated with lower relationship satisfaction, the behavioral mechanisms driving this link have remained unclear. In a week-long daily diary study involving 246 participants, researchers identified specific negative and positive behaviors in romantic relationships.... Read more »
  • Lowering Blood Pressure May Cut Dementia Risk by Up to 15%
    A massive study in rural China found that intensively lowering blood pressure significantly reduces the risk of dementia and cognitive decline in people with hypertension. Over 48 months, patients who received targeted care saw a 15% reduction in dementia and a 16% drop in cognitive impairment risk.... Read more »
  • Brain ‘Reset Wave’ May Explain How ECT Rapidly Relieves Depression
    Electroconvulsive therapy (ECT), long misunderstood due to outdated portrayals, remains the most effective treatment for severe, treatment-resistant mental illness. While traditionally thought to work solely through induced seizures, new research reveals that ECT also triggers a second brain event: cortical spreading depolarization (CSD).... Read more »

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