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    Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents

  • In This Issue
    Proceedings of the National Academy of Sciences, Volume 122, Issue 12, March 2025. <br/>... Read more »
  • Primitive homochiral polyester formation driven by tartaric acid and calcium availability
    Proceedings of the National Academy of Sciences, Volume 122, Issue 12, March 2025. <br/>SignificanceUnderstanding the origins of biological homochirality remains a fundamental challenge in prebiotic chemistry. Our research highlights the pivotal role of simple inorganic ions, such as Ca2+, in shaping the chiral selection and polymerization ...... Read more »
  • Isolated steady solutions of the 3D Euler equations
    Proceedings of the National Academy of Sciences, Volume 122, Issue 12, March 2025. <br/>SignificanceIn the study of the stationary incompressible fluid flows, one finds a subtle interplay between flexibility and rigidity properties, that is, between the existence of a wealth of solutions and the significant constraints that they must ...... Read more »
  • BCFW tilings and cluster adjacency for the amplituhedron
    Proceedings of the National Academy of Sciences, Volume 122, Issue 12, March 2025. <br/>SignificanceScattering amplitudes in a quantum field theory describe probabilities of different outcomes when particles interact. In 2005, Britto, Cachazo, Feng, and Witten gave a recurrence for computing scattering amplitudes inN= 4 super Yang–Mills ...... Read more »
  • Accelerated peptide bond formation at air–water interfaces
    Proceedings of the National Academy of Sciences, Volume 122, Issue 12, March 2025. <br/>SignificancePeptides and proteins lie at the heart of biological function, but molecular-level details of how their fundamental building blocks—amino acids—linked together under prebiotic conditions remain unclear. Herein, we unveil a unique isomerization-...... Read more »
  • ETV5 reduces androgen receptor expression and induces neural stem–like properties during neuroendocrine prostate cancer development
    Proceedings of the National Academy of Sciences, Volume 122, Issue 12, March 2025. <br/>SignificanceProstate cancer typically relies on male hormones for growth; however, prolonged hormone therapy can lead to a more aggressive form known as neuroendocrine prostate cancer (NEPC), which is resistant to treatment. This study identifies E26 ...... Read more »
  • Decoding in-cell respiratory enzyme dynamics by label-free in situ electrochemistry
    Proceedings of the National Academy of Sciences, Volume 122, Issue 12, March 2025. <br/>SignificanceUnderstanding enzyme function in living organisms is vital for advancing biochemistry and therapeutic strategies. However, traditional in vivo enzyme assays have primarily focused on enzymes unrelated to complex respiration. This study ...... Read more »

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UNIVERSITY OF SOUTHAMPTON

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    SciTechDaily

  • Scientists Capture First-Ever Image of Plasma’s Spaghetti-Like Instability
    For the first time, scientists have “photographed” a rare plasma instability, where high-energy electron beams form into spaghetti-like filaments. A recent study published in Physical Review Letters details how researchers used a high-intensity infrared laser to trigger a phenomenon known as filamentation instability, an effect with important implications for plasma-based... Read more »
  • Tiny Fossils Reveal Mammals Left the Trees Long Before the Asteroid Impact
    Millions of years before the asteroid impact that ended the reign of the dinosaurs, mammals were already beginning to shift from tree-dwelling to ground-based lifestyles. A groundbreaking study uncovered this evolutionary trend by analyzing tiny limb bone fragments from marsupials and placental mammals in Western North America. These subtle fossil... Read more »
  • The Cholesterol Sweet Spot That Shields Your Brain From Dementia
    Lowering your “bad” cholesterol might be doing more than just protecting your heart, it could also be safeguarding your brain. A large study found that people with low LDL cholesterol had a significantly lower risk of developing dementia, including Alzheimer’s disease. The effect was especially strong when LDL levels were... Read more »
  • Hidden Heart Risks: Antidepressants Linked to Sudden Cardiac Death
    Long-term antidepressant use is linked to a significantly increased risk of sudden cardiac death, especially in people under 60. Sudden cardiac death (SCD) is defined as an unexpected death due to a heart-related cause. It typically occurs within one hour of symptom onset in witnessed cases, or within 24 hours... Read more »
  • Challenging Existing Theories: Jupiter-Like Exoplanets Formed Much Sooner Than We Thought
    A new study challenges traditional models of how planets form. A new analysis of existing data suggests that exoplanets with masses comparable to Jupiter may have formed significantly earlier than previously believed. The study, conducted by researchers at The Ohio State University, offers fresh insight into the timing of accretion,... Read more »
  • Plastic Supercapacitors Could Help Solve the Energy Crisis
    A new method produces PEDOT nanofibers with enhanced electrical conductivity and increased surface area for improved charge storage. UCLA chemists have developed a new textured, fur-like version of PEDOT, a conductive plastic commonly used to protect electronics from static and in devices like solar cells and electrochromic displays. This innovative... Read more »
  • Disrupted Protein Balance: The Surprising Key to Autism Symptoms
    Scientists studying mice have uncovered a delicate protein rivalry in the brain that, when thrown off balance, may cause autism-like behaviors. This discovery opens up a potentially powerful new path for autism treatment by targeting how nerve signals are regulated at the molecular level. Protein Imbalance Tied to Autism Symptoms... Read more »

JOHNS HOPKINS UNIVERSITY

MESON STARS

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NEUROSCIENCE NEWS

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    Neuroscience News

  • Maternal Inflammation May Disrupt Infant Brain Wiring
    A new study reveals that inflammation during pregnancy may impair neurodevelopment in infants by reducing CD11c-positive microglia—key immune cells that support brain myelination. These cells produce IGF-1, a protein critical for forming the myelin sheath that helps nerve signals travel efficiently.... Read more »
  • AI Thinks Like Us: Flaws, Biases, and All, Study Finds
    A new study finds that ChatGPT, while excellent at logic and math, exhibits many of the same cognitive biases as humans when making subjective decisions. In tests for common judgment errors, the AI showed overconfidence, risk aversion, and even the classic gambler’s fallacy, though it avoided other typical human mistakes... Read more »
  • Protein Imbalance Triggers Autism-Like Behavior
    A new study reveals that autism-like symptoms in mice emerge when two nerve proteins—MDGA2 and BDNF—fall out of balance. MDGA2 typically keeps BDNF/TrkB signaling in check, but when MDGA2 levels drop, heightened neuronal activity and social impairments occur.... Read more »
  • Brain Mapping Tool Reveals How Learning Rewires Synaptic Links
    Researchers have developed DELTA, a powerful new imaging method that maps brain-wide synaptic changes during learning. By labeling synaptic proteins before and after behavioral training, scientists can now visualize where and how neural connections shift over time.... Read more »
  • Childhood Adversity Dulls Joy and Deepens Daily Emotional Swings
    A new study reveals that adverse childhood experiences make adults more emotionally reactive—not only to negative events, but also to positive ones.... Read more »
  • Brain Circuit for Vicarious Fear Reveals How We Feel Others’ Pain
    Scientists have uncovered a dedicated brain circuit that distinguishes between direct fear and fear learned by observing others—known as vicarious fear. The study shows that the right side of the brainstem’s locus coeruleus (LC) activates a specific pathway to the anterior cingulate cortex (ACC) during vicarious fear, while the left... Read more »
  • Psychedelics May Enhance Intimacy, Attraction, and Sexual Expression
    In the first study of its kind, researchers found that psychedelic use can positively affect sexuality, romantic relationships, and gender expression. Surveying nearly 600 users of substances like psilocybin, LSD, and ketamine, the study revealed that many participants reported increased partner attraction, improved intimacy, and enhanced sexual experiences.... Read more »

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